The health benefits and healing properties of herbal products have been known since ancient times. A number of epidemiological and laboratory studies conducted abroad revealed the biological effects and medicinal properties of shambala. In recent years, research on shambala has revealed a number of health benefits and physiological properties in both experimental animals and human clinical trials. In this research, we reviewed the available scientific literature on shambala.
Topicality and demand of the subject of dissertation. Development of science and intensification of all branches of national economy and also introduction of new technogenic processes of production have resulted in antropogenic influence of industrial activity of man on the environment and ecological equilibrium According to the data of regional evaluation of stable toxical compounds in the countries of the European Counsel the highest concentrations of Pb, Cd and Hg in the environment have been noted in the Ukraine (Pb-31,02; Cd-54, Hg-36 ton/year).Release of heavy metals to the environment for Russia equaled Pb-50%; Cd-66%; Hg-37% and in some others countries: Pb-10%,Cd-21%,Hg-58%,.Short analysis of the situation interms of these tree toxical metals has shown the level of antropogenic throwings of heavy toxical metals(HTM).The biggest part of HTM finding with throwings released to the atmosphere thrown out on soil and in waters of the country being the-surce the release and then they accumulate in neighbouring countries .
At presente time in the Republic of Uzbekistan the level of manufacture is rapidly growing and this results in the increase of the concervation of HTM compared with global scale of some natural processes. The most dangerous for the health of population are the non-essencial elements (Hg, Cd, Pb, As) . For this reason the monitoring of pollutions of objects of environment especialy HTM has acquired special importance and actuality. Qualitative and quantitative determination of ions of HTM has acquired important and necessary demands and has pulled out before analysts and ecologists the task of elaboration of express sensitive and selective methods of determination of microquantities of these elements which are dangerous toxicants, cancerogens and mutagens.
In this regard in the process protection of objects of the environment it is important and necessary to determinetion precise concentrations of HTM by different physical, chemical and physico-chemicals methods. For the practical realization of this problem at chemical analysis it is necessary to improve perfection existing methods analysis and elaborationof new modern methods ecotoxicants monitoring (espessially HTM). In the aspect of realization of theoretical prerequisites and practical confirmation of analytical determination of ecotoxicants concentrations it is necessary to elaborate some new hybrid methods with immobilization of different complexe-forming reagents on polymeric bearers and matrixes differing by high meteological and operation parameters.
Existing actual problems can be solved by introducing to the analytical practices of the methods of HTM determination of some new selective and specific organic reagents.The most perspective way of their solution is the purposeful synthesis and immobilization of new organic reagents with some definite analytical characteristics with following forecast of their properties with the aim of the optimal solving of the given tasks.
Elaboration of methods and approaches of prognosis as method of further development of sorbtion-spectroscopical method of analysis is an actual problem .In this range of theoretical and applied analytical chemistry there are considerable achivments bonding with investigations of home and forcing investigators ,but row of questions of problematical character has demanded of deep investigation and knowledges of new approaches and methods of their decision.
It is known that theory of action of OR is characterized as “system of ideas” allow ing to construct of some analytical system to find optimal by nature reagent and medium in which analytical reaction will carried out .In decision of some taskes of development of theory of OR action the fallowing stages neussarg to take into acconnl:”esplantion of observe processes and phenoments:prediction and direction works by synthesis of reagents with given properties .’’Thus the elaborated methodology and predication of properties of immobilized analytical reagents can be consider as definite seintific contribution in development of theory of action of IMOR for their using in analytical chemistry and ecology.
Purpose of research is elaboration of express, high-sensitive sorbtion-spectroscopical methods and test-systems of HTM determination with using of IMOR. Elaboration on the base of these methods some general approach to prognosis of properties and construction of specifical analytical grouos in organic reagents immobilized on different types of bearers synthesis of new organic reagents with given up properties on the base of our theretical prognosisesand introduction of them in practice of analysis of different analytical and ecological laboratories.
To achieve this goal the following tasks of research is solved: -optimization of immobilization conditions of organic reagents with preservation of their analytical properties; determination of mechanism of coloured reactious of complex-formation of immobilized organic reagents with ions of HTM;
-determination of connection between structure of OR and their analytical characteristics; prognosis of some perspective ways of their modification and directed synthesis of new specifical reagents on the base of nitronaphtols;
-analytical groups (EAG): (6-methyl-pyridil-2-azo-aminophenol; l-(5-methyl -2-pyridilfzo )-5-diethglaminophenol ;l-(4-antipyridilazo) -2-napthol sulphoacid; 1-(2-pyridilazo)-2-oxynaphtalin-6-sulphoacid sodlium; 3-hydroxy-4-nitrozo-2-naphtoic acid;2-hydroxiy -3-nitrozo naphtaldehyde and others);
-determination of influence of different factors and parameters on value of the analytical signal ;wing of elaborated methods in analysis of different by nature model binary ,triple and more complex mixtabiological objects industrial materials
-comparison of obtained results with results obtained by existing methods of determination of the investisated metals in solution.
Scientific novelty of disscrtational research consists in the following:
-Immobilization of different by nature reagents for prognosis and prediction of optimal construction of some OR based on quantum-chemical value of changing of analytical characteristics in dependence on structure of the functional and analytical-active groups has been theoretically based and practically has been realized;
-Chemico-analytical properties of OR immobilized on bearers on the base of polyacrylonitrile (PAN) and polypropylene (PP) for apriory prediction of structure of different OR and elaboration on their base an optical chemical sensors on the base PAN and PP-matrixes having some necessary analytical parameters;
Conclusion
1. Litrature date about using fiber sorbents and ion-exchanging on their base for determination of HTM cations at analysis objects of environment have been summarized. Advantages of using of fiber sorbents in comparison with their using as granule and powder have been shown. Necessarily of search of new immobilized reagents for determination metals in different objects was ground.
2. New scientific trend in analytical chemistry based on the sorbtion-spectroscopical determination of HTM in different objects of enviroment with using immobilized on fiber material organical reagents of different nature with aim of improvment of metrological parameters, exploitational and analytical parameters was developed.
3. Pysico-chemical and analytical properties of immobilized reagents on the base of reagents Arsenaza and threephenylmethan row and also synthesized on the department of organical chemistry NUUz sorbited on the fiber “Nitron” were systematically investigated. Optimal conditions of immobilization of new reagents on some polymeric bearers with preservation of theirspecifical analytical properties were determined.
4. 1R- spectroskopical investigation of immobilized reagents of fiber sorbents and their complexes with cations of HTM was carriedout. It was proved that in complex-formation of HTM ions with immobilized reagents the same functional analytical groups participated as in case of native solutions.
5. Results of investigations of interaction of reagents group Arsenazo and theephenylmethanic raw and also reagents synthesized on the derailment of inorganical and analytical chemistry of chemical faculty ofNUUz immobilized on marix on the base of PAN and PP-fibers with ions of HTM have shown that their immobilization was carried out owing to ionic changing and also formation of strong intermolecular hydrogenous bonds with bearers.
6. Using of calculating quant- chemical methods such as EMN, MNDO, RMZ and AM-1 has allowed in apriori to predict the structures of different rengents having some necessary analytical parameters (sensibility, contrastion of reactions and conditions of their carring out).
7. On the base on comparison optimal conditions of immobilization, sorbtion, degree of extraction of metals ions, coefficients of distribution, sorbtion capasity of fiber sorbents, data about sensibility of the analytical action occording to ions Cd, Hg, Cu and Fe in presence of accompanying elements, possibilities of quantitative desorption by small volumes of mineral acids and accessibility of initialcompounds it is shown an perspective of practical using of synthesized reagents and fiber sorbents. Immobilized reagents quantitativly have extracted ions of metals during 20-30 min at temperature 20-25°C in pH diapazone 3-7 (R=90-99%).
8. Coplex of methods of solidphase - spectroshopical and visually-testing determination of HTM in natural objects and samples of sewage and also new effective method of sorbtion - spectroskopical determination of Co,Cu, Cu, Ni, Fe and Hg in drinking and natural waters with using of immobilized organical reagent has been elaborated . This sorbtion - spectroskopical method has allowed to determine abovementioned metals in drinking and natural waters on the level n x 10-6 - n x 10'3 % and also to decrease the limitof their determination . Rightness of elaborated methods was proved by method “introduced - determined” at analysis of some real abjects and also by comparison with data obtained by atom -absorbtion method.
9. Elaborated methods were aprobated at analysis of real objects and were introduced in practics of laboratories by investigation of surface waters NYSMY; SES (sanepidemic station) of Tashkent region and Bekabad; department of radiopreparates of INP (Institute of nucleur physies) and others. Some obtained experimental data have been introduced in educational process at reading of lectures , carring out seminars and labaratory works with bachelors and masters by courses : “Analysis of environment objects”; “Optical methods of analysis “ ; “Physical methods of analysis “ ; “ Metrology statistics and computer in analytical chemistry” on the departments ofNUUz ; SamSU; Term.SV Tash.Pharm.1.
This article presents the characteristics of spill grunts, their types,methods of geological exploration, shurfs, their depth and hajmi, distance between shurfs, methods of mining shurfs and their impact on the physicochemical properties of spill grunts, the presence of large additives and gaps in spill grunts and their deposition, biracial static or Dynamic probing to determine these, exploratory drilling and work on obtaining samples to research the physicochemical properties of.
Dorivor o’simliklar tibbiyotda katta ahamiyatga ega. Dorivor o’simliklardan qadim zamonlardan buyon foydalanib kelingan. Hozirgi davrga kelib juda ko’plab kimyoviy dori vositalari ishlab chiqilgan. Lekin ular o'z navbatida ayrim kasalliklarni davolash bilan bir qatorda salbiy ta'siri ham kuzatilmoqda. Bu esa yana dirivor o'sumliklarga bo'lgan talabni oshirmoqda. Kimyoviy usullar bilan sintez qilib bo'lmaydigan biologik faol moddalar faqat o'simliklar tarkibida uchrashi olimlarni dorivor o'simliklarga bo'lgan qiziqishini orttirdi. Hozirgi zamonda dorivor o'simliklar ilmini rivojlantirish muhim vazifalardan biri. Dorivor o'simliklar bo'yicha olib borilayaotgan ilmiy tadqiqot ishlari eng kerakli va samarali dori vositalarini yaratishdan iborat. Ko'pchilik zamondoshlarimiz fikricha asal -o'tmishning tugallangan mavzusi. Sintetik kimyoda yuz minglab tabiatda hali mavjud bo'lmagan organik birikmalar, turli xil dorilar yaratilishi kimyoviy sintezning naqadar qudratliligini ko'rsatib berdi. Ammo o'tgan asrlar insoniyatning eski do'sti - asal ham bu dorilardan qolishmasligi olimlar tomonidan isbotlandi. Asal asrlar davomida insoniyat tomonidan shifobaxsh vosita sifatida ishlatilgan. Uning bu xususiyati uning tarkibidagi aminokislotalar,fermentlar,vitaminlar, turli xil mikroelementlar va organizmda suyak to'qimasining asosiy komponenti bo'lgan kalsiy samarali o'zlashtirilishida yordam berishi bilan bog'liq.
The clinical, functional and biomechanical properties of the fibrous membrane of the eye in children with
primary congenital glaucoma were studied using the method of elastotonometry. The results of a study of the
clinical, functional and biomechanical properties of the eyes in 57 children with primary congenital glaucoma and
in 11 healthy children aged 8 days to 7 years in the eye department of the clinic of the Tashkent Pediatric Medical
Institute are analyzed. Research methods included clinical and functional methods and special (to determine the
rigidity of the membranes of the eye). The results of the study showed that with an increase in elastopod values,
the indicators of corneal deformation decrease as a result of pronounced corneal edema; the level of IOP in the
advanced and terminal stages indicates the weak rigid properties of the fibrous membrane of the eye. Thus, the
elastotonometry method is an objective quantitative diagnostic criterion for assessing the biomechanical proper-
ties of the fibrous membrane of the eye in children with congenital glaucoma.
Tea is a unique concentrate of the most valuable taste, dietary and medicinal substances. Not a single drink has such a rich complex of biologically valuable, healing qualities. The therapeutic and prophylactic effect of tea makes it one of the important means of modern medicine. Along with alkaloids (caffeine, theobromine and theophylline), which give the drink a stimulating effect, tea leaves contain biologically valuable substances: tannin, various vitamins, trace elements, essential oils, soluble nitrogenous compounds and all essential amino acids. It contains many different phenolic compounds that give the drink unique healing properties and the current level of knowledge about the composition of tea helps to find objective criteria for determining its quality and move from the categories of subjective organoleptic and aesthetic assessments to a short and dispassionate language of numbers.
In this article, we can see the advantages of agiqtosh-mastic asphalt concrete coating and what features of it are given in depth to adapt it to the climatic conditions of Uzbekistan, and the effect of various stabilizing additives on the physical and mechanical properties of the mixture using the results of the study.
The scientific significance of the research results is explained by the determination of the influence of local raw materials and agricultural waste on the phase formation process and structure formation in ceramic wall material, as well as on its physical and mechanical properties and quality indicators under firing conditions
The article presents the results of experimental studies to study the effect on the physical and mechanical properties of foam concrete of the amount of microsilica microsilica of Uzmetkombinat JSC and polycarboxylate superplasticizer VESTA HPR 801 introduced into the composition as a mineral filler. It was revealed that with an increase in the amount of microsilica in the composition of foam concrete to a certain value, the compressive strength of the material first decreases, and then sharply increases. In this regard, by analyzing the regression equation, the optimal values of the prescription indicators of the foam concrete composition were substantiated.